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・ Imidafenacin
・ Imidapril
・ Imidazenil
・ Imidazol-4-one-5-propionic acid
・ Imidazolate
・ Imidazole
・ Imidazole N-acetyltransferase
・ Imidazole-1-sulfonyl azide
・ Imidazoleacetate 4-monooxygenase
・ Imidazoleacetate—phosphoribosyldiphosphate ligase
・ Imidazoleglycerol-phosphate dehydratase
・ Imidazolidine
・ Imidazolidine (data page)
・ Imidazolidinyl urea
・ Imidazoline
Imidazoline receptor
・ Imidazolonepropionase
・ Imidazopyridine
・ Imidazoquinoline
・ Imidazothiazole
・ Imide
・ Imider
・ Imidic acid
・ Imidiwan
・ Imidocarb
・ Imidogen
・ Imidoyl chloride
・ IMIDRO
・ Imidugudu
・ Imielenko


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Imidazoline receptor : ウィキペディア英語版
Imidazoline receptor
Imidazoline receptors are the primary receptors on which clonidine and other imidazolines act.
==Classes==
There are three classes of imidazoline receptors:〔
* I1 receptor – mediates the sympatho-inhibitory actions of imidazolines to lower blood pressure, (NISCH or IRAS, imidazoline receptor antisera selected)
* I2 receptor – an allosteric binding site of monoamine oxidase and is involved in pain modulation and neuroprotection
* I3 receptor – regulates insulin secretion from pancreatic beta cells
Activated I1-imidazoline receptors trigger the hydrolysis of phosphatidylcholine into DAG. Elevated DAG levels in turn trigger the synthesis of second messengers arachidonic acid and downstream eicosanoids. In addition, the sodium-hydrogen antiporter is inhibited, and enzymes of catecholamine synthesis are induced. The I1-imidazoline receptor may belong to the neurocytokine receptor family, since its signaling pathways are similar to those of interleukins.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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